Innomech Delivers for Aston Particle Size
25 October 2017APT is developing a one-step particle engineering technology to enable ‘challenging’ active pharmaceutical ingredients to be dry powder coated onto carrier particles: without needing heat, solvents or pressure. Target applications for this processing technology breakthrough include the development of new dry powder inhaler formulations, improving the solubility of poorly water-soluble drugs, and developing taste-masking solutions for bitter-tasting drugs.
Innomech has designed the new easy-to-use system to process up to two kilograms of pharmaceutical powders which is a 100-fold increase on the capacity of APT’s existing lab-scale, proof of principle equipment. The system provides a fluidised environment for particle contact and adsorption of cohesive material over coarse particles without the need for solvent and heat. Pressure and temperature sensors, and an ultra-efficient heat exchanger are used to monitor and maintain the required process conditions. http://www.innomech.co.uk/category/blog